diff --git a/maths/power_of_two.py b/maths/power_of_two.py
new file mode 100644
index 000000000000..bcd31a77143b
--- /dev/null
+++ b/maths/power_of_two.py
@@ -0,0 +1,31 @@
+"""
+Check if an integer is a power of two.
+
+Time Complexity: O(1)
+Space Complexity: O(1)
+"""
+
+
+def is_power_of_two(n: int) -> bool:
+    """Return True if n is a power of two (n > 0).
+
+    >>> is_power_of_two(1)
+    True
+    >>> is_power_of_two(2)
+    True
+    >>> is_power_of_two(3)
+    False
+    >>> is_power_of_two(0)
+    False
+    >>> is_power_of_two(-4)
+    False
+    """
+    if not isinstance(n, int):
+        raise TypeError("n must be an integer")
+    return n > 0 and (n & (n - 1)) == 0
+
+
+if __name__ == "__main__":
+    import doctest
+
+    doctest.testmod()