diff --git a/src/imageLoader/internal/xhrRequest.js b/src/imageLoader/internal/xhrRequest.js
index 0eb50da9..b3714dc8 100644
--- a/src/imageLoader/internal/xhrRequest.js
+++ b/src/imageLoader/internal/xhrRequest.js
@@ -21,6 +21,7 @@ function xhrRequest(url, imageId, defaultHeaders = {}, params = {}) {
     const xhr = new XMLHttpRequest();
 
     xhr.open('get', url, true);
+
     const beforeSendHeaders = options.beforeSend(
       xhr,
       imageId,
@@ -39,6 +40,7 @@ function xhrRequest(url, imageId, defaultHeaders = {}, params = {}) {
       if (key === 'Accept' && url.indexOf('accept=') !== -1) {
         return;
       }
+
       xhr.setRequestHeader(key, headers[key]);
     });
 
diff --git a/src/imageLoader/wadors/getPixelData.js b/src/imageLoader/wadors/getPixelData.js
index afade193..7e1bc769 100644
--- a/src/imageLoader/wadors/getPixelData.js
+++ b/src/imageLoader/wadors/getPixelData.js
@@ -1,6 +1,6 @@
 import { xhrRequest } from '../internal/index.js';
 import findIndexOfString from './findIndexOfString.js';
-
+import { multipartAcceptHeaderFieldValue } from '../../shared/mediaTypesUtils/multipartAcceptHeaderFieldValue.js';
 function findBoundary(header) {
   for (let i = 0; i < header.length; i++) {
     if (header[i].substr(0, 2) === '--') {
@@ -29,9 +29,9 @@ function uint8ArrayToString(data, offset, length) {
   return str;
 }
 
-function getPixelData(uri, imageId, mediaType = 'application/octet-stream') {
+function getPixelData(uri, imageId) {
   const headers = {
-    Accept: mediaType,
+    Accept: multipartAcceptHeaderFieldValue,
   };
 
   return new Promise((resolve, reject) => {
diff --git a/src/imageLoader/wadors/loadImage.js b/src/imageLoader/wadors/loadImage.js
index 9fd63a54..44615448 100644
--- a/src/imageLoader/wadors/loadImage.js
+++ b/src/imageLoader/wadors/loadImage.js
@@ -1,7 +1,6 @@
 import external from '../../externalModules.js';
 import getPixelData from './getPixelData.js';
 import createImage from '../createImage.js';
-
 /**
  * Helper method to extract the transfer-syntax from the response of the server.
  * @param {string} contentType The value of the content-type header as returned by the WADO-RS server.
@@ -72,21 +71,14 @@ function loadImage(imageId, options = {}) {
   const promise = new Promise((resolve, reject) => {
     // TODO: load bulk data items that we might need
 
-    // Uncomment this on to test jpegls codec in OHIF
-    // const mediaType = 'multipart/related; type="image/x-jls"';
-    // const mediaType = 'multipart/related; type="application/octet-stream"; transfer-syntax="image/x-jls"';
-    const mediaType =
-      'multipart/related; type=application/octet-stream; transfer-syntax=*';
-    // const mediaType =
-    //   'multipart/related; type="image/jpeg"; transfer-syntax=1.2.840.10008.1.2.4.50';
-
-    function sendXHR(imageURI, imageId, mediaType) {
+    function sendXHR(imageURI, imageId) {
       // get the pixel data from the server
-      return getPixelData(imageURI, imageId, mediaType)
+      return getPixelData(imageURI, imageId)
         .then((result) => {
           const transferSyntax = getTransferSyntaxForContentType(
             result.contentType
           );
+
           const pixelData = result.imageFrame.pixelData;
           const imagePromise = createImage(
             imageId,
@@ -115,7 +107,7 @@ function loadImage(imageId, options = {}) {
     const uri = imageId.substring(7);
 
     imageRetrievalPool.addRequest(
-      sendXHR.bind(this, uri, imageId, mediaType),
+      sendXHR.bind(this, uri, imageId),
       requestType,
       additionalDetails,
       priority,
diff --git a/src/shared/mediaTypesUtils/assertMediaTypeIsValid.js b/src/shared/mediaTypesUtils/assertMediaTypeIsValid.js
new file mode 100644
index 00000000..ab525caa
--- /dev/null
+++ b/src/shared/mediaTypesUtils/assertMediaTypeIsValid.js
@@ -0,0 +1,26 @@
+/**
+ * Asserts that a given media type is valid.
+ *
+ * @params {String} mediaType media type
+ */
+
+export default function assertMediaTypeIsValid(mediaType) {
+  if (!mediaType) {
+    throw new Error(`Not a valid media type: ${mediaType}`);
+  }
+  const sepIndex = mediaType.indexOf('/');
+
+  if (sepIndex === -1) {
+    throw new Error(`Not a valid media type: ${mediaType}`);
+  }
+  const mediaTypeType = mediaType.slice(0, sepIndex);
+
+  const types = ['application', 'image', 'text', 'video'];
+
+  if (!types.includes(mediaTypeType)) {
+    throw new Error(`Not a valid media type: ${mediaType}`);
+  }
+  if (mediaType.slice(sepIndex + 1).includes('/')) {
+    throw new Error(`Not a valid media type: ${mediaType}`);
+  }
+}
diff --git a/src/shared/mediaTypesUtils/mediaTypeJLL.js b/src/shared/mediaTypesUtils/mediaTypeJLL.js
new file mode 100644
index 00000000..e2b5ecaa
--- /dev/null
+++ b/src/shared/mediaTypesUtils/mediaTypeJLL.js
@@ -0,0 +1,4 @@
+const jllMediaType = 'image/jll';
+const jllTransferSyntaxUIDlossless = '1.2.840.10008.1.2.4.70';
+
+export { jllMediaType, jllTransferSyntaxUIDlossless };
diff --git a/src/shared/mediaTypesUtils/mediaTypeJLS.js b/src/shared/mediaTypesUtils/mediaTypeJLS.js
new file mode 100644
index 00000000..53e0d697
--- /dev/null
+++ b/src/shared/mediaTypesUtils/mediaTypeJLS.js
@@ -0,0 +1,5 @@
+const jlsMediaType = 'image/jls';
+const jlsTransferSyntaxUIDlossless = '1.2.840.10008.1.2.4.80';
+const jlsTransferSyntaxUID = '1.2.840.10008.1.2.4.81';
+
+export { jlsMediaType, jlsTransferSyntaxUIDlossless, jlsTransferSyntaxUID };
diff --git a/src/shared/mediaTypesUtils/mediaTypeJP2.js b/src/shared/mediaTypesUtils/mediaTypeJP2.js
new file mode 100644
index 00000000..9bc56417
--- /dev/null
+++ b/src/shared/mediaTypesUtils/mediaTypeJP2.js
@@ -0,0 +1,5 @@
+const jp2MediaType = 'image/jp2';
+const jp2TransferSyntaxUIDlossless = '1.2.840.10008.1.2.4.90';
+const jp2TransferSyntaxUID = '1.2.840.10008.1.2.4.91';
+
+export { jp2MediaType, jp2TransferSyntaxUIDlossless, jp2TransferSyntaxUID };
diff --git a/src/shared/mediaTypesUtils/mediaTypeJPEG.js b/src/shared/mediaTypesUtils/mediaTypeJPEG.js
new file mode 100644
index 00000000..616a12ec
--- /dev/null
+++ b/src/shared/mediaTypesUtils/mediaTypeJPEG.js
@@ -0,0 +1,11 @@
+const jpegMediaType = 'image/jpeg';
+const jpegTransferSyntaxUIDlossy1 = '1.2.840.10008.1.2.4.50';
+const jpegTransferSyntaxUIDlossy2 = '1.2.840.10008.1.2.4.51';
+const jpegTransferSyntaxUIDlossless = '1.2.840.10008.1.2.4.57';
+
+export {
+  jpegMediaType,
+  jpegTransferSyntaxUIDlossy1,
+  jpegTransferSyntaxUIDlossy2,
+  jpegTransferSyntaxUIDlossless,
+};
diff --git a/src/shared/mediaTypesUtils/mediaTypeOctetStream.js b/src/shared/mediaTypesUtils/mediaTypeOctetStream.js
new file mode 100644
index 00000000..8f7190ef
--- /dev/null
+++ b/src/shared/mediaTypesUtils/mediaTypeOctetStream.js
@@ -0,0 +1,4 @@
+const octetStreamMediaType = 'application/octet-stream';
+const octetStreamTransferSyntaxUID = '*';
+
+export { octetStreamMediaType, octetStreamTransferSyntaxUID };
diff --git a/src/shared/mediaTypesUtils/mediaTypeXDicomRLE.js b/src/shared/mediaTypesUtils/mediaTypeXDicomRLE.js
new file mode 100644
index 00000000..265e213c
--- /dev/null
+++ b/src/shared/mediaTypesUtils/mediaTypeXDicomRLE.js
@@ -0,0 +1,4 @@
+const xdicomrleMediaType = 'image/x-dicom-rle';
+const xdicomrleTransferSyntaxUID = '1.2.840.10008.1.2.5';
+
+export { xdicomrleMediaType, xdicomrleTransferSyntaxUID };
diff --git a/src/shared/mediaTypesUtils/mediaTypes.js b/src/shared/mediaTypesUtils/mediaTypes.js
new file mode 100644
index 00000000..b585a11b
--- /dev/null
+++ b/src/shared/mediaTypesUtils/mediaTypes.js
@@ -0,0 +1,73 @@
+import {
+  xdicomrleMediaType,
+  xdicomrleTransferSyntaxUID,
+} from './mediaTypeXDicomRLE.js';
+import {
+  jpegMediaType,
+  jpegTransferSyntaxUIDlossy1,
+  jpegTransferSyntaxUIDlossy2,
+  jpegTransferSyntaxUIDlossless,
+} from './mediaTypeJPEG.js';
+import { jllMediaType, jllTransferSyntaxUIDlossless } from './mediaTypeJLL.js';
+import {
+  jlsMediaType,
+  jlsTransferSyntaxUID,
+  jlsTransferSyntaxUIDlossless,
+} from './mediaTypeJLS.js';
+import {
+  jp2MediaType,
+  jp2TransferSyntaxUID,
+  jp2TransferSyntaxUIDlossless,
+} from './mediaTypeJP2.js';
+import {
+  octetStreamMediaType,
+  octetStreamTransferSyntaxUID,
+} from './mediaTypeOctetStream.js';
+
+// NOTE: the position of the elements in the array indicates the mediaType
+// priority when fetching an image. An element at the beginning of the array
+// has the highest priority.
+const mediaTypes = [
+  {
+    mediaType: xdicomrleMediaType,
+    transferSyntaxUID: xdicomrleTransferSyntaxUID,
+  },
+  {
+    mediaType: jpegMediaType,
+    transferSyntaxUID: jpegTransferSyntaxUIDlossy1,
+  },
+  {
+    mediaType: jpegMediaType,
+    transferSyntaxUID: jpegTransferSyntaxUIDlossy2,
+  },
+  {
+    mediaType: jpegMediaType,
+    transferSyntaxUID: jpegTransferSyntaxUIDlossless,
+  },
+  {
+    mediaType: jllMediaType,
+    transferSyntaxUID: jllTransferSyntaxUIDlossless,
+  },
+  {
+    mediaType: jlsMediaType,
+    transferSyntaxUID: jlsTransferSyntaxUIDlossless,
+  },
+  {
+    mediaType: jlsMediaType,
+    transferSyntaxUID: jlsTransferSyntaxUID,
+  },
+  {
+    mediaType: jp2MediaType,
+    transferSyntaxUID: jp2TransferSyntaxUIDlossless,
+  },
+  {
+    mediaType: jp2MediaType,
+    transferSyntaxUID: jp2TransferSyntaxUID,
+  },
+  {
+    mediaType: octetStreamMediaType,
+    transferSyntaxUID: octetStreamTransferSyntaxUID,
+  },
+];
+
+export { mediaTypes };
diff --git a/src/shared/mediaTypesUtils/multipartAcceptHeaderFieldValue.js b/src/shared/mediaTypesUtils/multipartAcceptHeaderFieldValue.js
new file mode 100644
index 00000000..f236bd2d
--- /dev/null
+++ b/src/shared/mediaTypesUtils/multipartAcceptHeaderFieldValue.js
@@ -0,0 +1,50 @@
+import assertMediaTypeIsValid from './assertMediaTypeIsValid.js';
+import { mediaTypes } from './mediaTypes.js';
+
+/**
+ * Builds an accept header field value for HTTP GET multipart request messages.
+ *
+ * Takes in input a media types array of type [{mediaType, transferSyntaxUID}, ... ]
+ * and finally composes a string for the accept header field value as in example below:
+ *
+ * "multipart/related; type="image/x-dicom-rle"; transfer-syntax=1.2.840.10008.1.2.5,
+ *  multipart/related; type="image/jpeg"; transfer-syntax=1.2.840.10008.1.2.4.50,
+ *  multipart/related; type="application/octet-stream"; transfer-syntax=*"
+ *
+ * NOTE: the xhr request will try to fetch with all the transfer-syntax syntaxes
+ * specified in the accept header field value in descending order.
+ * The first element ("image/x-dicom-rle" in this example) has the highest priority.
+ *
+ * @param {Array} mediaTypes Acceptable media types
+ *
+ * @returns {string} accept header field value
+ */
+
+export default function buildMultipartAcceptHeaderFieldValue(mediaTypes) {
+  if (!Array.isArray(mediaTypes)) {
+    throw new Error('Acceptable media types must be provided as an Array');
+  }
+
+  const fieldValueParts = [];
+
+  mediaTypes.forEach((item) => {
+    const { transferSyntaxUID, mediaType } = item;
+
+    assertMediaTypeIsValid(mediaType);
+
+    let fieldValue = `multipart/related; type="${mediaType}"`;
+
+    if (transferSyntaxUID) {
+      fieldValue += `; transfer-syntax=${transferSyntaxUID}`;
+    }
+
+    fieldValueParts.push(fieldValue);
+  });
+
+  return fieldValueParts.join(', ');
+}
+
+const multipartAcceptHeaderFieldValue =
+  buildMultipartAcceptHeaderFieldValue(mediaTypes);
+
+export { multipartAcceptHeaderFieldValue };