diff --git a/.github/actions/run_examples_using_pypi_uploads/action.yml b/.github/actions/run_examples_using_pypi_uploads/action.yml
index f112987cb..d46cb5dc9 100644
--- a/.github/actions/run_examples_using_pypi_uploads/action.yml
+++ b/.github/actions/run_examples_using_pypi_uploads/action.yml
@@ -15,7 +15,7 @@ runs:
   steps:
     # The local wheel installation and single environment would have made using tox-system_tests.ini difficult.
     # To keep things simple, we just use pip and pytest directly for a single Python version.
-    - run: py -3.12 -m venv --clear .venv
+    - run: py -3.13 -m venv --clear .venv
       shell: powershell
     - run: |
         .venv\Scripts\Activate.ps1
diff --git a/.travis.yml b/.travis.yml
index 39a66604f..d231b62bf 100644
--- a/.travis.yml
+++ b/.travis.yml
@@ -3,12 +3,15 @@ language: python
 dist: focal
 matrix:
     include:
-      # We run tests on the latest supported version of Python first.
+      # Historically, we've run tests on the latest supported version of Python first.
+      # For now, we're running Python 3.12 first, because it's the version currently used for codegen.
       # This is where additional tests are run so we give it more time.
+      # When the version used for codegen changes, the version that runs first should change to match.
       - python: "3.12"
       - python: "3.9"
       - python: "3.10"
       - python: "3.11"
+      - python: "3.13"
 
 install:
   - travis_retry sudo apt-get -y install python3-pip
@@ -18,7 +21,8 @@ install:
   - travis_retry pip install --upgrade tox==3.* tox-travis
 
 before_script:
-  - python tools/ensure_codegen_up_to_date.py
+  # Python 3.13 is only supported by grpcio-tools >= 1.67.0, a later version than what we use in the tox.ini
+  - if [[ "$TRAVIS_PYTHON_VERSION" != "3.13" ]]; then python tools/ensure_codegen_up_to_date.py; fi
 
 script:
   - tox -c tox-travis.ini
diff --git a/CHANGELOG.md b/CHANGELOG.md
index 24b51fb89..f829835fb 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -38,6 +38,7 @@ All notable changes to this project will be documented in this file.
 ## Unreleased
 * ### ALL
     * #### Added
+        * Support for Python 3.13
     * #### Changed
         * Fix [#2069](https://github.com/ni/nimi-python/issues/2069)
     * #### Removed
diff --git a/build/templates/setup.py.mako b/build/templates/setup.py.mako
index e9f05f726..6c921be1c 100644
--- a/build/templates/setup.py.mako
+++ b/build/templates/setup.py.mako
@@ -46,7 +46,7 @@ setup(
     extras_require={
         'grpc': [
             'grpcio>=1.59.0,<2.0',
-            'protobuf>=4.21.6,<5.0'
+            'protobuf>=4.21.6'
         ],
     },
     % endif
@@ -63,6 +63,7 @@ setup(
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/build/templates/tox-system_tests.ini.mako b/build/templates/tox-system_tests.ini.mako
index cd3f27d5a..4070299d6 100644
--- a/build/templates/tox-system_tests.ini.mako
+++ b/build/templates/tox-system_tests.ini.mako
@@ -11,7 +11,7 @@
         wheel_env_no_py = '{}-wheel_dep'.format(module_name)
         # We only actually need to build it once, but we specify multiple versions here
         # to prevent tox from trying to build the wheel with an unsupported (earlier) Python version
-        wheel_env = 'py{39,310,311,312}-' + wheel_env_no_py + ','
+        wheel_env = 'py{39,310,311,312,313}-' + wheel_env_no_py + ','
         uses_other_wheel = True
         if module_name == 'nitclk':
             # nitclk system tests use niscope
@@ -28,7 +28,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/${module_name})
 [tox]
-envlist = ${wheel_env}py{39,310,311,312}-${module_name}-system_tests, py312-${module_name}-coverage
+envlist = ${wheel_env}py{39,310,311,312,313}-${module_name}-system_tests, py313-${module_name}-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -87,7 +87,7 @@ deps =
     ${module_name}-coverage: coverage
 
 depends =
-    ${module_name}-coverage: py{39,310,311,312}-${module_name}-system_tests
+    ${module_name}-coverage: py{39,310,311,312,313}-${module_name}-system_tests
 % if uses_other_wheel:
     ${module_name}-system_tests: ${wheel_env}
 % endif
diff --git a/generated/nidcpower/setup.py b/generated/nidcpower/setup.py
index b91691c21..064352292 100644
--- a/generated/nidcpower/setup.py
+++ b/generated/nidcpower/setup.py
@@ -36,7 +36,7 @@ def read_contents(file_to_read):
     extras_require={
         'grpc': [
             'grpcio>=1.59.0,<2.0',
-            'protobuf>=4.21.6,<5.0'
+            'protobuf>=4.21.6'
         ],
     },
     classifiers=[
@@ -52,6 +52,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/nidcpower/tox-system_tests.ini b/generated/nidcpower/tox-system_tests.ini
index a10b36735..2fc11e0b7 100644
--- a/generated/nidcpower/tox-system_tests.ini
+++ b/generated/nidcpower/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/nidcpower)
 [tox]
-envlist = py{39,310,311,312}-nidcpower-system_tests, py312-nidcpower-coverage
+envlist = py{39,310,311,312,313}-nidcpower-system_tests, py313-nidcpower-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -43,7 +43,7 @@ deps =
     nidcpower-coverage: coverage
 
 depends =
-    nidcpower-coverage: py{39,310,311,312}-nidcpower-system_tests
+    nidcpower-coverage: py{39,310,311,312,313}-nidcpower-system_tests
 
 passenv =
     GIT_BRANCH
diff --git a/generated/nidigital/setup.py b/generated/nidigital/setup.py
index 33bea8ae5..37238ce24 100644
--- a/generated/nidigital/setup.py
+++ b/generated/nidigital/setup.py
@@ -37,7 +37,7 @@ def read_contents(file_to_read):
     extras_require={
         'grpc': [
             'grpcio>=1.59.0,<2.0',
-            'protobuf>=4.21.6,<5.0'
+            'protobuf>=4.21.6'
         ],
     },
     classifiers=[
@@ -53,6 +53,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/nidigital/tox-system_tests.ini b/generated/nidigital/tox-system_tests.ini
index 4bcef3a22..a0e1d4f9c 100644
--- a/generated/nidigital/tox-system_tests.ini
+++ b/generated/nidigital/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/nidigital)
 [tox]
-envlist = py{39,310,311,312}-nidigital-wheel_dep,py{39,310,311,312}-nidigital-system_tests, py312-nidigital-coverage
+envlist = py{39,310,311,312,313}-nidigital-wheel_dep,py{39,310,311,312,313}-nidigital-system_tests, py313-nidigital-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -50,8 +50,8 @@ deps =
     nidigital-coverage: coverage
 
 depends =
-    nidigital-coverage: py{39,310,311,312}-nidigital-system_tests
-    nidigital-system_tests: py{39,310,311,312}-nidigital-wheel_dep,
+    nidigital-coverage: py{39,310,311,312,313}-nidigital-system_tests
+    nidigital-system_tests: py{39,310,311,312,313}-nidigital-wheel_dep,
 
 passenv =
     GIT_BRANCH
diff --git a/generated/nidmm/setup.py b/generated/nidmm/setup.py
index 62bb6aa65..1dec9caa2 100644
--- a/generated/nidmm/setup.py
+++ b/generated/nidmm/setup.py
@@ -36,7 +36,7 @@ def read_contents(file_to_read):
     extras_require={
         'grpc': [
             'grpcio>=1.59.0,<2.0',
-            'protobuf>=4.21.6,<5.0'
+            'protobuf>=4.21.6'
         ],
     },
     classifiers=[
@@ -52,6 +52,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/nidmm/tox-system_tests.ini b/generated/nidmm/tox-system_tests.ini
index 3a3f88b93..87bdc8e6f 100644
--- a/generated/nidmm/tox-system_tests.ini
+++ b/generated/nidmm/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/nidmm)
 [tox]
-envlist = py{39,310,311,312}-nidmm-system_tests, py312-nidmm-coverage
+envlist = py{39,310,311,312,313}-nidmm-system_tests, py313-nidmm-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -43,7 +43,7 @@ deps =
     nidmm-coverage: coverage
 
 depends =
-    nidmm-coverage: py{39,310,311,312}-nidmm-system_tests
+    nidmm-coverage: py{39,310,311,312,313}-nidmm-system_tests
 
 passenv =
     GIT_BRANCH
diff --git a/generated/nifake/setup.py b/generated/nifake/setup.py
index cb551df17..1e696a4b0 100644
--- a/generated/nifake/setup.py
+++ b/generated/nifake/setup.py
@@ -37,7 +37,7 @@ def read_contents(file_to_read):
     extras_require={
         'grpc': [
             'grpcio>=1.59.0,<2.0',
-            'protobuf>=4.21.6,<5.0'
+            'protobuf>=4.21.6'
         ],
     },
     classifiers=[
@@ -53,6 +53,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/nifake/tox-system_tests.ini b/generated/nifake/tox-system_tests.ini
index b7be0467e..540b2bd20 100644
--- a/generated/nifake/tox-system_tests.ini
+++ b/generated/nifake/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/nifake)
 [tox]
-envlist = py{39,310,311,312}-nifake-wheel_dep,py{39,310,311,312}-nifake-system_tests, py312-nifake-coverage
+envlist = py{39,310,311,312,313}-nifake-wheel_dep,py{39,310,311,312,313}-nifake-system_tests, py313-nifake-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -50,8 +50,8 @@ deps =
     nifake-coverage: coverage
 
 depends =
-    nifake-coverage: py{39,310,311,312}-nifake-system_tests
-    nifake-system_tests: py{39,310,311,312}-nifake-wheel_dep,
+    nifake-coverage: py{39,310,311,312,313}-nifake-system_tests
+    nifake-system_tests: py{39,310,311,312,313}-nifake-wheel_dep,
 
 passenv =
     GIT_BRANCH
diff --git a/generated/nifgen/setup.py b/generated/nifgen/setup.py
index 6c0c9b489..c140bbc9d 100644
--- a/generated/nifgen/setup.py
+++ b/generated/nifgen/setup.py
@@ -37,7 +37,7 @@ def read_contents(file_to_read):
     extras_require={
         'grpc': [
             'grpcio>=1.59.0,<2.0',
-            'protobuf>=4.21.6,<5.0'
+            'protobuf>=4.21.6'
         ],
     },
     classifiers=[
@@ -53,6 +53,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/nifgen/tox-system_tests.ini b/generated/nifgen/tox-system_tests.ini
index 1572fbc08..ca9a84c27 100644
--- a/generated/nifgen/tox-system_tests.ini
+++ b/generated/nifgen/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/nifgen)
 [tox]
-envlist = py{39,310,311,312}-nifgen-wheel_dep,py{39,310,311,312}-nifgen-system_tests, py312-nifgen-coverage
+envlist = py{39,310,311,312,313}-nifgen-wheel_dep,py{39,310,311,312,313}-nifgen-system_tests, py313-nifgen-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -50,8 +50,8 @@ deps =
     nifgen-coverage: coverage
 
 depends =
-    nifgen-coverage: py{39,310,311,312}-nifgen-system_tests
-    nifgen-system_tests: py{39,310,311,312}-nifgen-wheel_dep,
+    nifgen-coverage: py{39,310,311,312,313}-nifgen-system_tests
+    nifgen-system_tests: py{39,310,311,312,313}-nifgen-wheel_dep,
 
 passenv =
     GIT_BRANCH
diff --git a/generated/nimodinst/setup.py b/generated/nimodinst/setup.py
index 02c8fb049..59efa3822 100644
--- a/generated/nimodinst/setup.py
+++ b/generated/nimodinst/setup.py
@@ -46,6 +46,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/nimodinst/tox-system_tests.ini b/generated/nimodinst/tox-system_tests.ini
index f48dcebea..422c5918e 100644
--- a/generated/nimodinst/tox-system_tests.ini
+++ b/generated/nimodinst/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/nimodinst)
 [tox]
-envlist = py{39,310,311,312}-nimodinst-system_tests, py312-nimodinst-coverage
+envlist = py{39,310,311,312,313}-nimodinst-system_tests, py313-nimodinst-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -42,7 +42,7 @@ deps =
     nimodinst-coverage: coverage
 
 depends =
-    nimodinst-coverage: py{39,310,311,312}-nimodinst-system_tests
+    nimodinst-coverage: py{39,310,311,312,313}-nimodinst-system_tests
 
 passenv =
     GIT_BRANCH
diff --git a/generated/niscope/setup.py b/generated/niscope/setup.py
index 3ebb546cf..2f61e270d 100644
--- a/generated/niscope/setup.py
+++ b/generated/niscope/setup.py
@@ -37,7 +37,7 @@ def read_contents(file_to_read):
     extras_require={
         'grpc': [
             'grpcio>=1.59.0,<2.0',
-            'protobuf>=4.21.6,<5.0'
+            'protobuf>=4.21.6'
         ],
     },
     classifiers=[
@@ -53,6 +53,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/niscope/tox-system_tests.ini b/generated/niscope/tox-system_tests.ini
index a2a99de8e..a6a59b6a0 100644
--- a/generated/niscope/tox-system_tests.ini
+++ b/generated/niscope/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/niscope)
 [tox]
-envlist = py{39,310,311,312}-niscope-wheel_dep,py{39,310,311,312}-niscope-system_tests, py312-niscope-coverage
+envlist = py{39,310,311,312,313}-niscope-wheel_dep,py{39,310,311,312,313}-niscope-system_tests, py313-niscope-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -50,8 +50,8 @@ deps =
     niscope-coverage: coverage
 
 depends =
-    niscope-coverage: py{39,310,311,312}-niscope-system_tests
-    niscope-system_tests: py{39,310,311,312}-niscope-wheel_dep,
+    niscope-coverage: py{39,310,311,312,313}-niscope-system_tests
+    niscope-system_tests: py{39,310,311,312,313}-niscope-wheel_dep,
 
 passenv =
     GIT_BRANCH
diff --git a/generated/nise/setup.py b/generated/nise/setup.py
index 79b5eaf6c..735df6b4c 100644
--- a/generated/nise/setup.py
+++ b/generated/nise/setup.py
@@ -46,6 +46,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/nise/tox-system_tests.ini b/generated/nise/tox-system_tests.ini
index 04fabd029..7c5b7adb0 100644
--- a/generated/nise/tox-system_tests.ini
+++ b/generated/nise/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/nise)
 [tox]
-envlist = py{39,310,311,312}-nise-system_tests, py312-nise-coverage
+envlist = py{39,310,311,312,313}-nise-system_tests, py313-nise-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -42,7 +42,7 @@ deps =
     nise-coverage: coverage
 
 depends =
-    nise-coverage: py{39,310,311,312}-nise-system_tests
+    nise-coverage: py{39,310,311,312,313}-nise-system_tests
 
 passenv =
     GIT_BRANCH
diff --git a/generated/niswitch/setup.py b/generated/niswitch/setup.py
index 9cad4ee76..04d9c59b2 100644
--- a/generated/niswitch/setup.py
+++ b/generated/niswitch/setup.py
@@ -36,7 +36,7 @@ def read_contents(file_to_read):
     extras_require={
         'grpc': [
             'grpcio>=1.59.0,<2.0',
-            'protobuf>=4.21.6,<5.0'
+            'protobuf>=4.21.6'
         ],
     },
     classifiers=[
@@ -52,6 +52,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/niswitch/tox-system_tests.ini b/generated/niswitch/tox-system_tests.ini
index e8c6f8afd..7b7527617 100644
--- a/generated/niswitch/tox-system_tests.ini
+++ b/generated/niswitch/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/niswitch)
 [tox]
-envlist = py{39,310,311,312}-niswitch-system_tests, py312-niswitch-coverage
+envlist = py{39,310,311,312,313}-niswitch-system_tests, py313-niswitch-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -43,7 +43,7 @@ deps =
     niswitch-coverage: coverage
 
 depends =
-    niswitch-coverage: py{39,310,311,312}-niswitch-system_tests
+    niswitch-coverage: py{39,310,311,312,313}-niswitch-system_tests
 
 passenv =
     GIT_BRANCH
diff --git a/generated/nitclk/setup.py b/generated/nitclk/setup.py
index 216466c63..8890cfd98 100644
--- a/generated/nitclk/setup.py
+++ b/generated/nitclk/setup.py
@@ -46,6 +46,7 @@ def read_contents(file_to_read):
         "Programming Language :: Python :: 3.10",
         "Programming Language :: Python :: 3.11",
         "Programming Language :: Python :: 3.12",
+        "Programming Language :: Python :: 3.13",
         "Programming Language :: Python :: Implementation :: CPython",
         "Topic :: System :: Hardware :: Hardware Drivers"
     ],
diff --git a/generated/nitclk/tox-system_tests.ini b/generated/nitclk/tox-system_tests.ini
index dd05deb4f..c360ec5e9 100644
--- a/generated/nitclk/tox-system_tests.ini
+++ b/generated/nitclk/tox-system_tests.ini
@@ -3,7 +3,7 @@
 # test suite on all supported python versions. To use it, "pip install tox"
 # and then run "tox -c tox-system_tests.ini" from the driver directory. (generated/nitclk)
 [tox]
-envlist = py{39,310,311,312}-nitclk-wheel_dep,py{39,310,311,312}-nitclk-system_tests, py312-nitclk-coverage
+envlist = py{39,310,311,312,313}-nitclk-wheel_dep,py{39,310,311,312,313}-nitclk-system_tests, py313-nitclk-coverage
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 # We put the .tox directory outside of the Jenkins workspace so that it isn't wiped with the rest of the repo
@@ -49,8 +49,8 @@ deps =
     nitclk-coverage: coverage
 
 depends =
-    nitclk-coverage: py{39,310,311,312}-nitclk-system_tests
-    nitclk-system_tests: py{39,310,311,312}-nitclk-wheel_dep,
+    nitclk-coverage: py{39,310,311,312,313}-nitclk-system_tests
+    nitclk-system_tests: py{39,310,311,312,313}-nitclk-wheel_dep,
 
 passenv =
     GIT_BRANCH
diff --git a/tox-travis.ini b/tox-travis.ini
index 8e3311b39..8f781ede1 100644
--- a/tox-travis.ini
+++ b/tox-travis.ini
@@ -6,10 +6,15 @@
 # tox.ini and tox-travis.ini are copies of the same content with different envlist commented out
 # tox-travis.ini will have pyXX-clean and all pyXX-installers in the default envlist, while the developer tox.ini
 # does not have clean and only has one pyXX-installers
+# Historically we've used the latest Python for environments that we only list one Python for. For now, we're using Python 3.12
+# to avoid updating our pb2 files, which could possibly cause incompatibilities with other NI Python packages.
+# When other NI Python packages bump the version that they use for generating pb2 files, we can bump this Python version to match.
+# We may also bump it sooner, if we agree with team members who own other NI Python packages that it's okay to do so.
+# At the latest, we'll bump it when we drop support for Python 3.12.
 # Uncomment this line for tox.ini
-# envlist = py312-build_test,py312-codegen,py312-installers,py{39,310,311,312}-test,py312-flake8,py312-docs,py312-pkg
+# envlist = py312-build_test,py312-codegen,py312-installers,py{39,310,311,312,313}-test,py312-flake8,py312-docs,py312-pkg
 # Uncomment this line for tox-travis.ini
-envlist = py312-clean,py312-build_test,py312-codegen,py{39,310,311,312}-installers,py{39,310,311,312}-test,py312-flake8,py312-docs,py312-pkg
+envlist = py312-clean,py312-build_test,py312-codegen,py{39,310,311,312,313}-installers,py{39,310,311,312,313}-test,py312-flake8,py312-docs,py312-pkg
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 skipsdist = true
@@ -136,8 +141,8 @@ deps =
     test: mako
     test: numpy
     test: hightime
-    test: grpcio == 1.59.0  # Compatible with grpcio-tools 1.59.0
-    test: protobuf == 4.21.6  # Compatible with grpcio-tools 1.59.0
+    test: grpcio == 1.67.0  # Compatible with Python 3.13; should be backwards compatible with grpcio-tools 1.59.0
+    test: protobuf == 5.27.2  # Compatible with Python 3.13; should be backwards compatible with grpcio-tools 1.59.0
     build_test: pytest
     build_test: coverage
     build_test: mako
@@ -145,7 +150,7 @@ deps =
     build_test: pep8-naming
     codegen: mako
     codegen: packaging
-    codegen: grpcio-tools == 1.59.0  # First version to support Python 3.12
+    codegen: grpcio-tools == 1.59.0 # First version to support Python 3.12
     installers: build
     flake8: hacking
     flake8: pep8-naming
diff --git a/tox.ini b/tox.ini
index a7cd94b32..0f9ec336f 100644
--- a/tox.ini
+++ b/tox.ini
@@ -6,10 +6,15 @@
 # tox.ini and tox-travis.ini are copies of the same content with different envlist commented out
 # tox-travis.ini will have pyXX-clean and all pyXX-installers in the default envlist, while the developer tox.ini
 # does not have clean and only has one pyXX-installers
+# Historically we've used the latest Python for environments that we only list one Python for. For now, we're using Python 3.12
+# to avoid updating our pb2 files, which could possibly cause incompatibilities with other NI Python packages.
+# When other NI Python packages bump the version that they use for generating pb2 files, we can bump this Python version to match.
+# We may also bump it sooner, if we agree with team members who own other NI Python packages that it's okay to do so.
+# At the latest, we'll bump it when we drop support for Python 3.12.
 # Uncomment this line for tox.ini
-envlist = py312-build_test,py312-codegen,py312-installers,py{39,310,311,312}-test,py312-flake8,py312-docs,py312-pkg
+envlist = py312-build_test,py312-codegen,py312-installers,py{39,310,311,312,313}-test,py312-flake8,py312-docs,py312-pkg
 # Uncomment this line for tox-travis.ini
-# envlist = py312-clean,py312-build_test,py312-codegen,py{39,310,311,312}-installers,py{39,310,311,312}-test,py312-flake8,py312-docs,py312-pkg
+# envlist = py312-clean,py312-build_test,py312-codegen,py{39,310,311,312,313}-installers,py{39,310,311,312,313}-test,py312-flake8,py312-docs,py312-pkg
 skip_missing_interpreters=True
 ignore_basepython_conflict=True
 skipsdist = true
@@ -136,8 +141,8 @@ deps =
     test: mako
     test: numpy
     test: hightime
-    test: grpcio == 1.59.0  # Compatible with grpcio-tools 1.59.0
-    test: protobuf == 4.21.6  # Compatible with grpcio-tools 1.59.0
+    test: grpcio == 1.67.0  # Compatible with Python 3.13; should be backwards compatible with grpcio-tools 1.59.0
+    test: protobuf == 5.27.2  # Compatible with Python 3.13; should be backwards compatible with grpcio-tools 1.59.0
     build_test: pytest
     build_test: coverage
     build_test: mako
@@ -145,7 +150,7 @@ deps =
     build_test: pep8-naming
     codegen: mako
     codegen: packaging
-    codegen: grpcio-tools == 1.59.0  # First version to support Python 3.12
+    codegen: grpcio-tools == 1.59.0 # First version to support Python 3.12
     installers: build
     flake8: hacking
     flake8: pep8-naming