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atach_function adds a class variable. So, you can write code like the following. This was not well documented in the Ruby-FFI wiki.
atach_function
def bcf_itr_querys(idx, hdr, s) hts_itr_querys(idx, s, @@bcf_hdr_name2id, hdr, @@hts_itr_query, @@bcf_readrec) end